Once you can afford the Ranch (or if you can afford it because you didn't overspend on slaves), buy it, as the products made will far outshine the costs males can be milked from the start, but females will need lactation and nectar potions to do so. There are temporary ones as well as permanent ones. Start with the former but transition to the latter asap. Loyalty increases as you train them and they actively participate in their training. Their fear will hit fearless first (granting the uncommon title 'Fearless Slave'), long before their obedience, simply because it has a far smaller variable limit, while most slaves will be disobedient or even defiant to start, at the far end of obedience. Eventually it'll tick over to unswervingly subservient, at which point you'll earn the title 'Loyal Slave'. Honestly, you'll get them to perfect stats long before you'll get them to reach loyal you'd be better off focussing on getting them the Feminine title, which restores 20% fatigue every week, instead.